A futuristic Inquisition ruthlessly hunts down anyone with even the slightest taint of the heretic, the mutant, or the alien, even going as far as destroying entire planets, just to be sure. The Space Marines (capricious, fanatical, genetically engineered Knight Templar Super Soldiers) and the Sisters of Battle (equally fanatical, pyromaniacal battle nuns) serve as the Imperium's special forces, while the Imperial Guard, its at least trillions-strong regular army, takes disregard for human life to new and interesting extremes.
Since then, he has become the godhead of the Imperium, and the incomprehensibly vast Ecclesiarchy spreads the Imperial Cult and commits horrible atrocities in his name (but against his philosophy) on an almost-daily basis. Its leader, known only as the Emperor, was betrayed and laid low by his most beloved son, and for more than ten millennia has been locked up in an arcane life support mechanism that anchors his soul in his withered corpse and requires the souls of psychic humans to be consumed in the thousands per day as fuel. In the waning years of the 41st millennium, the game's central faction, the Imperium of Man, is a paranoid, fascist theocratic state which spans the galaxy but is struggling mightily to maintain its grip on its territory. In the distant past, humanity held immeasurable power and glory, but no longer.
